SS3R Antibody - #DF2778
Product: | SS3R Antibody |
Catalog: | DF2778 |
Description: | Rabbit polyclonal antibody to SS3R |
Application: | WB IHC |
Reactivity: | Human |
Prediction: | Rat, Pig, Bovine, Sheep |
Mol.Wt.: | 46 kDa; 46kD(Calculated). |
Uniprot: | P32745 |
RRID: | AB_2839984 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2778, RRID:AB_2839984.
Fold/Unfold
OTTHUMP00000028737; Smstr 3; Smstr3; Somatostatin receptor subtype 3; Somatostatin receptor type 3; SS 3R; SS-3-R; SS3-R; SS3R; SSR 28; SSR-28; SSR28; SSR3_HUMAN; Sst 3; Sst3; SSTR 3; SSTR3;
Immunogens
- P32745 SSR3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P32745 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
R71 | Methylation | Uniprot | |
Y142 | Phosphorylation | Uniprot | |
Y303 | Phosphorylation | Uniprot | |
S332 | Phosphorylation | Uniprot | |
S337 | Phosphorylation | Uniprot | |
T341 | Phosphorylation | Uniprot | |
T348 | Phosphorylation | Uniprot | |
S361 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.
Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity).
Cell membrane>Multi-pass membrane protein.
Note: Internalized into endoplasmic vesicles upon somatostatin-stimulation.
Brain, pituitary and pancreas.
Homodimer and heterodimer with SSTR2. Heterodimerization with SSTR2 inactivates SSTR3 receptor function (By similarity).
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
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