AMBRA1 Antibody - #DF6228
Product: | AMBRA1 Antibody |
Catalog: | DF6228 |
Description: | Rabbit polyclonal antibody to AMBRA1 |
Application: | WB IHC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
Mol.Wt.: | 133kDa; 143kD(Calculated). |
Uniprot: | Q9C0C7 |
RRID: | AB_2838194 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF6228, RRID:AB_2838194.
Fold/Unfold
Activating molecule in beclin 1 regulated autophagy; Activating molecule in BECN1 regulated autophagy protein 1; Activating molecule in BECN1-regulated autophagy protein 1; Ambra1; AMRA1_HUMAN; FLJ20294; Hypothetical protein FLJ20294; Hypothetical protein LOC55626; KIAA1736; MGC33725; WDR94;
Immunogens
- Q9C0C7 AMRA1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVGEQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTAECCQHLGILCLCSRCSGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTRTVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVPSSFESVPSSGSQLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQSSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMRYQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVPRRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVHSNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPEPGTAASGPGEGEGSEYGASGEDALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9C0C7 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
Phosphorylation | Uniprot | ||
K2 | Ubiquitination | Uniprot | |
K7 | Ubiquitination | Uniprot | |
K36 | Ubiquitination | Uniprot | |
K41 | Ubiquitination | Uniprot | |
S52 | Phosphorylation | P42345 (MTOR) | Uniprot |
K175 | Ubiquitination | Uniprot | |
R226 | Methylation | Uniprot | |
S328 | Phosphorylation | Uniprot | |
S387 | Phosphorylation | Uniprot | |
T391 | Phosphorylation | Uniprot | |
R392 | Methylation | Uniprot | |
S394 | Phosphorylation | Uniprot | |
S443 | Phosphorylation | Uniprot | |
S465 | Phosphorylation | Uniprot | |
S628 | Phosphorylation | Uniprot | |
S629 | Phosphorylation | Uniprot | |
S635 | Phosphorylation | Uniprot | |
S639 | Phosphorylation | Uniprot | |
S696 | Phosphorylation | Uniprot | |
S722 | Phosphorylation | Uniprot | |
R730 | Methylation | Uniprot | |
R747 | Methylation | Uniprot | |
R754 | Methylation | Uniprot | |
R795 | Methylation | Uniprot | |
S797 | Phosphorylation | Uniprot | |
S800 | Phosphorylation | Uniprot | |
R808 | Methylation | Uniprot | |
Y814 | Phosphorylation | Uniprot | |
R824 | Methylation | Uniprot | |
Y1026 | Phosphorylation | Uniprot | |
T1028 | Phosphorylation | Uniprot | |
S1043 | Phosphorylation | Uniprot | |
S1192 | Phosphorylation | Uniprot | |
T1203 | Phosphorylation | Uniprot | |
S1204 | Phosphorylation | Uniprot | |
S1205 | Phosphorylation | Uniprot | |
T1238 | Phosphorylation | Uniprot |
Research Backgrounds
Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity).
Cytoplasmic vesicle>Autophagosome.
Note: Localizes also to discrete punctae along the ciliary axoneme.
Interacts with BECN1. Probably forms a complex with BECN1 and PIK3C3 (By similarity). Interacts with BECN2.
Research Fields
· Cellular Processes > Transport and catabolism > Autophagy - animal. (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.