Product: SERC1 Mouse Monoclonal Antibody
Catalog: BF8654
Description: Mouse monoclonal antibody to SERC1
Application: WB
Reactivity: Human
Prediction: Mouse, Rat
Mol.Wt.: 48kDa; 50kD(Calculated).
Uniprot: Q9NRX5

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 100ul $280 In stock
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Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8654]
Specificity:
SERC1 Mouse Monoclonal Antibody detects endogenous levels of total SERC1.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

1500011D18Rik; AI315070; AIGP 2; KIAA1253; LRRGT00191; mKIAA1253; SERC1_HUMAN; SERINC1; Serine incorporator 1; TDE1L; TDE2; TMS 2; Tms2; Tumor differentially expressed 1 protein like; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2; UNQ396/PRO732;

Immunogens

Immunogen:

A synthesized peptide derived from human SERC1, corresponding to a region within C-terminal amino acids.

Uniprot:
Gene(ID):
Description:
SERINC1 Enhances the incorporation of serine into phosphatidylserine and sphingolipids. Belongs to the TDE1 family. Interacts with SPTLC1.
Sequence:
MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD

PTMs - Q9NRX5 As Substrate

Site PTM Type Enzyme
G2 Myristoylation
S31 Phosphorylation
S35 Phosphorylation
T36 Phosphorylation
T38 Phosphorylation
N298 N-Glycosylation
K343 Ubiquitination
T345 Phosphorylation
T347 Phosphorylation
S348 Phosphorylation
S351 Phosphorylation
T352 Phosphorylation
S361 Phosphorylation
S364 Phosphorylation
Y410 Phosphorylation
S413 Phosphorylation
S418 Phosphorylation
T421 Phosphorylation

Research Backgrounds

Function:

Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

Subcellular Location:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with SPTLC1.

Family&Domains:

Belongs to the TDE1 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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