Product: SCNM1 Mouse Monoclonal Antibody
Catalog: BF8652
Description: Mouse monoclonal antibody to SCNM1
Application: WB
Reactivity: Human
Prediction: Rat, Bovine, Horse, Sheep, Monkey
Mol.Wt.: 26 kDa; 26kD(Calculated).
Uniprot: Q9BWG6

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Mouse
Application:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Monoclonal [AFfirm8652]
Specificity:
SCNM1 Mouse Monoclonal Antibody detects endogenous levels of total SCNM1.
Conjugate:
Unconjugated.
Purification:
Affinity-chromatography.
Storage:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

SCNM 1; Sodium channel modifier 1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Sequence:
MSFKREGDDWSQLNVLKKRRVGDLLASYIPEDEALMLRDGRFACAICPHRPVLDTLAMLTAHRAGKKHLSSLQLFYGKKQPGKERKQNPKHQNELRREETKAEAPLLTQTRLITQSALHRAPHYNSCCRRKYRPEAPGPSVSLSPMPPSEVKLQSGKISREPEPAAGPQAEESATVSAPAPMSPTRRRALDHYLTLRSSGWIPDGRGRWVKDENVEFDSDEEEPPDLPLD

PTMs - Q9BWG6 As Substrate

Site PTM Type Enzyme
S2 Phosphorylation
K17 Ubiquitination
Y76 Phosphorylation
K101 Ubiquitination
S126 Phosphorylation
S144 Phosphorylation
S159 Phosphorylation
S183 Phosphorylation
Y193 Phosphorylation
T195 Phosphorylation
S219 Phosphorylation

Research Backgrounds

Function:

Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.

Subcellular Location:

Nucleus>Nucleoplasm. Nucleus speckle.
Note: Colocalizes with LUC7L2 and SNRNP70 in nuclear speckles.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Interacts with spliceosomal Sm proteins. Interacts with LUC7L2 and SNRNP70, which suggests a role as a spliceosome component (By similarity).

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