AMOTL1 Antibody - #DF12556
Product: | AMOTL1 Antibody |
Catalog: | DF12556 |
Description: | Rabbit polyclonal antibody to AMOTL1 |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Horse, Rabbit, Dog |
Mol.Wt.: | 107 kDa; 107kD(Calculated). |
Uniprot: | Q8IY63 |
RRID: | AB_2845518 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12556, RRID:AB_2845518.
Fold/Unfold
2310010G08Rik; 2310067L22Rik; 4932416D09Rik; AMOL1_HUMAN; Amotl1; Angiomotin-like protein 1; FLJ00155; JEAP; Junction enriched and associated protein; mFLJ00155;
Immunogens
- Q8IY63 AMOL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8IY63 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K16 | Ubiquitination | Uniprot | |
T51 | Phosphorylation | Uniprot | |
S52 | Phosphorylation | Uniprot | |
S61 | Phosphorylation | Uniprot | |
K174 | Ubiquitination | Uniprot | |
Y191 | Phosphorylation | Uniprot | |
K195 | Ubiquitination | Uniprot | |
S198 | Phosphorylation | Uniprot | |
Y218 | Phosphorylation | Uniprot | |
Y219 | Phosphorylation | Uniprot | |
T224 | Phosphorylation | Uniprot | |
S225 | Phosphorylation | Uniprot | |
K227 | Ubiquitination | Uniprot | |
S241 | Phosphorylation | Uniprot | |
K251 | Ubiquitination | Uniprot | |
S262 | Phosphorylation | Uniprot | |
S269 | Phosphorylation | Uniprot | |
K289 | Ubiquitination | Uniprot | |
S295 | Phosphorylation | Uniprot | |
K302 | Ubiquitination | Uniprot | |
K316 | Methylation | Uniprot | |
K316 | Ubiquitination | Uniprot | |
K318 | Methylation | Uniprot | |
K318 | Ubiquitination | Uniprot | |
S322 | Phosphorylation | Uniprot | |
K347 | Ubiquitination | Uniprot | |
T373 | Phosphorylation | Uniprot | |
S374 | Phosphorylation | Uniprot | |
K474 | Ubiquitination | Uniprot | |
S485 | Phosphorylation | Uniprot | |
K503 | Ubiquitination | Uniprot | |
K540 | Ubiquitination | Uniprot | |
Y546 | Phosphorylation | Uniprot | |
K551 | Ubiquitination | Uniprot | |
K594 | Ubiquitination | Uniprot | |
K611 | Ubiquitination | Uniprot | |
K625 | Ubiquitination | Uniprot | |
K649 | Ubiquitination | Uniprot | |
Y661 | Phosphorylation | Uniprot | |
K686 | Ubiquitination | Uniprot | |
K690 | Ubiquitination | Uniprot | |
T707 | Phosphorylation | Uniprot | |
T714 | Phosphorylation | Uniprot | |
T715 | Phosphorylation | Uniprot | |
S720 | Phosphorylation | Uniprot | |
S724 | Phosphorylation | Uniprot | |
K756 | Ubiquitination | Uniprot | |
K761 | Ubiquitination | Uniprot | |
K765 | Ubiquitination | Uniprot | |
K782 | Ubiquitination | Uniprot | |
S793 | Phosphorylation | P54646 (PRKAA2) | Uniprot |
S796 | Phosphorylation | Uniprot | |
T803 | Phosphorylation | Uniprot | |
S805 | Phosphorylation | Uniprot | |
S809 | Phosphorylation | Uniprot | |
S813 | Phosphorylation | Uniprot | |
S828 | Phosphorylation | Uniprot | |
S876 | Phosphorylation | Uniprot | |
T877 | Phosphorylation | Uniprot | |
T879 | Phosphorylation | Uniprot | |
S892 | Phosphorylation | Uniprot | |
S895 | Phosphorylation | Uniprot | |
S900 | Phosphorylation | Uniprot | |
T901 | Phosphorylation | Uniprot | |
T902 | Phosphorylation | Uniprot | |
S906 | Phosphorylation | Uniprot | |
T917 | Phosphorylation | Uniprot | |
S924 | Phosphorylation | Uniprot | |
S930 | Phosphorylation | Uniprot | |
S939 | Phosphorylation | Uniprot |
Research Backgrounds
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Polyubiquitinated by NEDD4, leading to proteasomal degradation.
Cell junction>Tight junction.
Belongs to the angiomotin family.
Research Fields
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
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