TA2R Antibody - #DF10271
Product: | TA2R Antibody |
Catalog: | DF10271 |
Description: | Rabbit polyclonal antibody to TA2R |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Mol.Wt.: | 37 kDa; 37kD(Calculated). |
Uniprot: | P21731 |
RRID: | AB_2840849 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF10271, RRID:AB_2840849.
Fold/Unfold
BDPLT13; Prostanoid TP receptor; TA2R_HUMAN; Tbxa2r; Thromboxane A2 receptor; TP receptor; TXA2 R; TXA2-R; TXA2R;
Immunogens
- P21731 TA2R_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
PTMs - P21731 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S118 | Phosphorylation | Uniprot | |
S128 | Phosphorylation | Uniprot | |
S145 | Phosphorylation | Uniprot | |
S239 | Phosphorylation | Uniprot | |
S324 | Phosphorylation | P17252 (PRKCA) | Uniprot |
S329 | Phosphorylation | P17612 (PRKACA) , P17252 (PRKCA) | Uniprot |
S331 | Phosphorylation | P17612 (PRKACA) , P17252 (PRKCA) | Uniprot |
T337 | Phosphorylation | P17252 (PRKCA) | Uniprot |
Research Backgrounds
Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase. Isoform 2 inhibits adenylyl cyclase.
Cell membrane>Multi-pass membrane protein.
Interacts with RPGRIP1L. Interacts with PSMA3. Interacts with RACK1; the interaction regulates TBXA2R cell surface expression.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Immune system > Platelet activation. (View pathway)
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.